Rescue teams have reached the spot. As per local media channel reports quoting eyewitnesses, at least two people have died and the toll is likely to rise.
Many are feared trapped. Some injured people were taken to hospitals. As many as 47 people have been admitted to Balasore Hospital alone, said media reports.
Visuals showed the many bodies of the train dismantled.
The train was en route from Kolkata to Chennai.
The train started its journey at 3.30 pm from West Bengal's Shalimar station and arrived at Balasore station at 6.30 pm. It was scheduled to reach Chennai at 4.50 pm on Saturday.
The Odisha Government has provided several helpline numbers -- 033-26382217, 8972073925, 67822 62286, 9332392339.